Key result
Although 30-day mortality after CABG and valve surgery decreased significantly over a 12-year period, 1-year mortality remained unchanged at 6.25% in 2011-2012 compared to 6.50% in 1999-2000.
Why the study?
Does the continued fall in short-term mortality after cardiac surgery reflect an actual improvement in 1-year mortality?
Cohort (n=25,602)
Yes
Does the continued fall in short-term mortality after cardiac surgery reflect an actual improvement in 1-year mortality?
Although 30-day mortality after CABG and valve surgery has significantly decreased over a 12-year period, 1-year mortality has remained constant, suggesting age has a greater impact on late mortality than baseline comorbidities.
Answers are grounded in this paper and cite their sources.
Improved short-term survival after cardiac surgery may not extend to 1 year; hypothesis-generating for age-focused strategies to reduce late mortality.
INTRODUCTION: European system for cardiac operative risk evaluation (EuroSCORE) is a valuable tool in control of the quality of cardiac surgery. However, the validity of the risk score for the individual patient may be questioned. The present study was carried out to investigate whether the continued fall in short-term mortality reflects an actual improvement in late mortality, and subsequently, to investigate EuroSCORE as predictor of 1-year mortality. METHODS: A population-based cohort study of 25,602 patients from a 12-year period from three public university hospitals undergoing coronary artery bypass grafting (CABG) or valve surgery. Analysis was carried out based on EuroSCORE, age and co-morbidity factors (residual EuroSCORE). RESULTS: During the period the average age increased from 65.1 ± 10.0 years to 68.9 ± 10.7 years (P < 0.001, one-way ANOVA), and the number of females increased from 26.0% to 28.2% (P = 0.0012, Chi-square test). The total EuroSCORE increased from 4.67 to 5.68 while the residual EuroSCORE decreased from 2.64 to 1.83. Thirty-day mortality decreased from 4.07% in 1999-2000 to 2.44% in 2011-2012 (P = 0.0056; Chi-square test), while 1-year mortality was unchanged (6.50% in 1999-2000 vs. 6.25% in 2011-2012 [P = 0.8086; Chi-square test]). DISCUSSION: The study demonstrates that both co-morbidity and age has a great impact on 30-day mortality. However, with time the impact of co-morbidity seems less. Thus, age is more important than co-morbidity in late mortality. The various developments in short and long-term mortality are not readily explained. CONCLUSION: Although 30-day mortality of CABG and valve surgery patients has decreased during the 12-year period, the 1-year mortality remains the same.
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Jakobsen et al. (2015) conducted a cohort in Patients undergoing coronary artery bypass grafting (CABG) or valve surgery (n=25,602). Cardiac surgery in 2011-2012 vs. Cardiac surgery in 1999-2000 was evaluated on 1-year mortality (p=0.8086). Although 30-day mortality after CABG and valve surgery decreased significantly over a 12-year period, 1-year mortality remained unchanged at 6.25% in 2011-2012 compared to 6.50% in 1999-2000.
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