Primary progressive aphasia

In recent years there has been increasing interest in individuals with gradual deterioration of language skills in the absence of generalized cognitive impairments or identifiable vascular, neoplastic, metabolic, or infectious aetiology. In this paper, we review the available data on primary progressive aphasia and summarize the demographic, behavioural, and neurological characteristics of those who have been presumed to have the disorder. We also discuss some of our own clinical observations and several issues related to increasing our understanding of the disorder and its differential diagnosis, description, and management.