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• 23 Na MRI enables the quantification of tissue sodium concentration (TSC). • TSC quantification is primarily performed based on external reference phantoms. • Internal references have the potential to simplify 23Na MR imaging. • CSF and the vitreous humor as internal references on 50 stroke patients. • Quantification based on the vitreous humor provided most robust results.
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Adlung et al. (2022) studied this question.
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