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Article1 October 1965Pulmonary CryptococcosisMust All Receive Amphotericin B?VERNON N. HOUK, KENNETH M. MOSER, M.D., F.A.C.P.VERNON N. HOUKSearch for more papers by this author, KENNETH M. MOSER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-4-583 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn the past cryptococcosis has been considered a rare disease usually terminating in highly fatal meningitis. Prior to 1955 about 300 cases had been reported (1). In recent years, localized pulmonary lesions attributable toCryptococcus neoformansoccurring in the absence of extrapulmonary infection have been diagnosed by microscopic and cultural examination of resected tissue obtained at the time of diagnostic thoractomy and have seldom been diagnosed clinically (2). This has been due to the lack of an available reliable skin test antigen and relatively meager experience with serologic studies (3). It also reflects failure to consider the disease in the...References1. JOHNSONSAICHEKJAMES GFHBLR: Pulmonary cryptococcosis. Nebraska Med. J. 46: 146, 1961. MedlineGoogle Scholar2. HAWKINS JA Cavitary pulmonary cryptococcosis. Amer. Rev. Resp. Dis. 84: 579, 1961. MedlineGoogle Scholar3. LITTMAN ML: Cryptococcosis (torulosis). Amer. J. Med. 27: 976, 1959. CrossrefMedlineGoogle Scholar4. WHITEARANY MLS: Resection in pulmonary cryptococcosis (torulosis). J. Thorac. Cardiov. Surg. 35: 402, 1958. Google Scholar5. BAHRSATZPURLA RDHVL: Primary pulmonary cryptococcosis. Amer. J. Roentgenol. 87: 859, 1962. Google Scholar6. KNUDSONBURCHHATCH RJHBHB: Primary pulmonary cryptococcosis. J. Thorac. Cardiov. Surg. 45: 730, 1963. CrossrefMedlineGoogle Scholar7. WILSON JW: Therapy of systemic fungus infections in 1961. Arch. Intern. Med. (Chicago) 108: 292, 1961. 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Amer. J. Clin. Path. 24: 1381, 1954. CrossrefMedlineGoogle Scholar23. STAUBFISHKINSCHWARZ MBGJ: Residual pulmonary lesions of fungal origin in Southern California. Mycopathologia 20: 55, 1963. Google Scholar24. LINDENSTEFFEN IHCG: Pulmonary cryptococcosis. Amer. Rev. Resp. Dis. 69: 116, 1954. Google Scholar25. GREENINGMENVILLE RBLJ: Roentgen findings in torulosis: report of four cases. Radiology 48: 381, 1947. CrossrefMedlineGoogle Scholar26. COLLINSGELLHORNTRUMBLE WPAJR: The coincidence of cryptococcosis and disease of the reticuloendothelial and lymphatic systems. Cancer 4: 883, 1951. CrossrefMedlineGoogle Scholar27. WEIDMAN FD: Discussion of paper by CRAWLEY, E. P., GREKIN, R. H., CURTIS, A. C.: Torulosis: a review of the cutaneous and adjoining mucous membrane manifestations. J. Invest. Derm. 14: 327, 1950. CrossrefMedlineGoogle Scholar28. LITTMANZIMMERMAN MLLE: Cryptococcus neoformans in pigeon excretion in New York City. Amer. J. Hyg. 69: 49, 1959. MedlineGoogle Scholar29. CHICK EW: Pulmonary fungal infections simulating and misdiagnosed as other diseases. Amer. Rev. Resp. Dis. 85: 702, 1962. MedlineGoogle Scholar30. LITTMANZIMMERMAN MLLE: Cryptococcosis, Torulosis or European Blastomycosis, Grune & Stratton Inc., New York, 1956. Google Scholar31. THOMASMCCLENATHANOSBORNE RCJEDP: Pulmonary cryptococcosis. Med. Ann. DC 31: 77, 1962. MedlineGoogle Scholar32. KRESSCANTRELL MBJR: Pulmonary and meningeal cryptococcosis: successful treatment of the meningitis with lateral cerebral intraventricular injection of amphotericin B. Arch. Intern. Med. (Chicago) 112: 386, 1963. CrossrefMedlineGoogle Scholar33. WOLFEJACOBSEN JNG: Roentgen manifestation of torulosis (cryptococcosis). Amer. J. Roentgen. 79: 216, 1958. Google Scholar34. REEVESBRITTHAMMACH DLEMRW: Torula infection of the lungs and central nervous system. Report of 6 cases with 3 autopsies. Arch. Intern. Med. (Chicago) 68: 57, 1947. CrossrefGoogle Scholar35. BERKGERSTL MB: Torulosis (cryptococcosis) producing a solitary pulmonary lesion: report of a 4 year case with lobectomy. JAMA 149: 1310, 1952. CrossrefGoogle Scholar36. BUTLERBENNETTALLINGWERTLAKEUTZHILL WTJEDWPTJPGJ: Nephrotoxicity of amphotericin B: early and late effect in 81 patients. Ann. Intern. Med. 61: 175, 1964. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Bethesda, Maryland, and Washington, D. C.From the Department of Medicine, U. S. Naval Hospital, National Naval Medical Center, Bethesda, Md., and Georgetown University Medical Center, Washington, D. C.This paper was presented at the Golden Anniversary Session of the American College of Physicians in Chicago, Ill., March 23.Requests for reprints should be addressed to Vernon N. Houk, CDR, MC USN, U. S. Naval Hospital, St. Albans, N. Y. 11425. 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FASS, M.D., ROBERT L. PERKINS, M.D., F.A.C.P.CryptococcosisCryptococcosisCryptococcosisPulmonary Cryptococcosis:The Spectrum of Pulmonary CryptococcosisWINSTON WARR, M.D., JOSEPH H. BATES, M.D., F.A.C.P., ALICE STONEVariant Forms of Pulmonary CryptococcosisBAYARD TYNES, M.D., F.A.C.P., KATHLEEN N. MASON, M.S., ANNE E. JENNINGS, JOHN E. BENNETT, M.D., F.A.C.P.Cryptococcosis: Current statusTreatment of disseminated mycotic infectionsDeep-Seated Mycotic Infections, Allergy to Fungi and MycotoxinsEpidemiologic Study of Cryptococcus neoformansW. MARCUS NEWBERRY JR., M.D., JINKS E. WALTER, D.V.M., DR.P.H., JOHN W. CHANDLER JR., M.D., FRED E. TOSH, M.D.Cryptococcosis—RevisitedRecognition and Current Management of the Systemic MycosesTwo cases of cryptococcosis 1 October 1965Volume 63, Issue 4Page: 583-596KeywordsAntigensCryptococcosisCryptococcus neoformansHospital medicineLesionsMeningitisPulmonary diseasesSkin tests Issue Published: 1 October 1965 PDF DownloadLoading ...
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