Enantioselective Synthesis of All‐Carbon Quaternary Stereogenic Centers by Catalytic Asymmetric Conjugate Additions of Alkyl and Aryl Aluminum Reagents to Five‐, Six‐, and Seven‐Membered‐Ring β‐Substituted Cyclic Enones

Solution to pesky problems: Effective methods for catalytic asymmetric conjugate additions of alkyl and aryl aluminum reagents with unactivated β-substituted cyclopentenones are now available (see scheme). Transformations, promoted by chiral bidentate N-heterocyclic carbene (NHC) copper complexes derived from 1, give rise to all-carbon quaternary stereogenic centers.