Key result
High-sensitivity CRP was strongly associated with 1-year myocardial infarction and death in nondiabetic patients with unstable angina (P=0.0012), but not in diabetic patients.
Why the study?
Does hsCRP predict the combined occurrence of myocardial infarction and death differently in diabetic versus nondiabetic patients with unstable angina?
Cohort (n=251)
Does hsCRP predict the combined occurrence of myocardial infarction and death differently in diabetic versus nondiabetic patients with unstable angina?
p-value: p=0.0012
hsCRP is a strong prognostic marker for MI and death in nondiabetic patients with unstable angina, but lacks prognostic value in those with type 2 diabetes, where coronary disease severity plays a larger role.
No takes yet. Share an insight, caveat, or question.
hsCRP may aid nondiabetic unstable angina risk stratification; leaves open its utility in diabetes and requires prospective validation.
Biasucci et al. (2009) conducted a cohort in Unstable angina (n=251). High-sensitivity C-reactive protein (hsCRP) was evaluated on Combined occurrence of myocardial infarction (MI) and death at 1 year (p=0.0012). High-sensitivity CRP was strongly associated with 1-year myocardial infarction and death in nondiabetic patients with unstable angina (P=0.0012), but not in diabetic patients.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: