An in vivo method is described for screening polymeric materials for biocompatibility. The test is based on grading acute and subacute tissue reactions at 7 and 28 days, respectively, following implantation in rats. The methods is reproducible and reliable. It is designed to provide uniform test criteria for biocompatibility assessment in the early phases of the development of surgical implant materials.
No takes yet. Share an insight, caveat, or question.
Gourlay et al. (1978) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: