Key result
Sudomotor dysfunction, assessed by absent sympathetic skin response, was significantly associated with increased odds of foot ulceration in patients with diabetes (OR 15.3; 95% CI 5.3-38.4).
Why the study?
Is sudomotor dysfunction associated with an increased risk of foot ulceration in patients with diabetes?
Population
90 patients with either Type 1 or Type 2 diabetes
Comparison
Sudomotor dysfunction vs Normal sudomotor function
Design
Cross-sectional
Authors
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May aid diabetic foot risk stratification; leaves open whether sudomotor testing alters outcomes in prospective trials.
Cross-Sectional (n=90)
Is sudomotor dysfunction associated with an increased risk of foot ulceration in patients with diabetes?
Odds Ratio: 15.3 (95% CI 5.3–38.4)
Sudomotor dysfunction, indicated by an absent sympathetic skin response, is strongly associated with foot ulceration in diabetic patients and could serve as a valuable screening tool.
Tentolouris et al. (2009) conducted a cross-sectional in Type 1 or Type 2 diabetes (n=90). Sudomotor dysfunction (absent sympathetic skin response) vs. Normal sudomotor function was evaluated on Foot ulceration (OR 15.3, 95% CI 5.3-38.4). Sudomotor dysfunction, assessed by absent sympathetic skin response, was significantly associated with increased odds of foot ulceration in patients with diabetes (OR 15.3; 95% CI 5.3-38.4).
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