Article1 October 1958SOME RECENT DEVELOPMENTS PERTAINING TO PANCREATITISJOHN B. GROSS, M.D.JOHN B. GROSS, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-49-4-796 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince the second century of the Christian era, when the pancreas was apparently considered by Galen to be a mechanical cushion for the stomach,1 knowledge regarding the structure and functions of this organ in both health and disease has advanced considerably. This knowledge has been derived from experimental as well as clinical and pathologic observations, and, although significant gaps remain, it is encouraging that new developments continue.It is intended to review here some of the recent developments pertaining to pancreatitis, first mentioning some observations regarding the natural history of the disease and then considering several interesting, if poorly understood,...Bibliography1. Coope R: The diagnosis of pancreatic disease, 1927, Oxford University Press, New York. CrossrefGoogle Scholar2. ComfortGambillBaggenstoss MWEEAH: Chronic relapsing pancreatitis: study of twenty-nine cases without associated disease of the biliary or gastro-intestinal tract, Gastroenterology 6: 239, 376, 1946. MedlineGoogle Scholar3. GambillComfortBaggenstoss EEMWAH: Chronic relapsing pancreatitis: an analysis of 27 cases associated with disease of the biliary tract, Gastroenterology 11: 1, 1948. MedlineGoogle Scholar4. Mayo JG: Pancreatic calculi, Proc. Staff Meet., Mayo Clin. 11: 456, 1936. Google Scholar5. SnellComfort AMMW: The incidence and diagnosis of pancreatic lithiasis: review of eighteen cases, Am. J. Digest. Dis. 8: 237, 1941. CrossrefGoogle Scholar6. Vachon MA: Les formes douloureuses des pancréatites chroniques, Lyon méd. 167: 333, 1942. Google Scholar7. MaimonKirsnerPalmer SHJBWL: Chronic recurrent pancreatitis: a clinical study of 20 cases, Arch. Int. Med. 81: 56, 1948. CrossrefGoogle Scholar8. EliasonWelty ELRF: Pancreatic calculi, Ann. Surg. 127: 150, 1948. CrossrefMedlineGoogle Scholar9. GambillPugh EEDG: Pancreatic calcification: study of clinical and roentgenologic data on thirty-nine cases, Arch. Int. Med. 81: 301, 1948. CrossrefGoogle Scholar10. BartholomewComfort LGMW: Chronic pancreatitis without pain, Gastroenterology 31: 727, 1956. CrossrefMedlineGoogle Scholar11. GrossComfort JBMW: Chronic pancreatitis, Am. J. Med. 21: 596, 1956. CrossrefMedlineGoogle Scholar12. GrossComfortWaugh JBMWJM: Painless single stone in pancreatic duct: report of a case with steatorrheal diarrhea, Gastroenterology 32: 126, 1957. CrossrefMedlineGoogle Scholar13. Wightman KJ: Diseases of the pancreas, M. Clin. North America 32: 518-536 (Mar.) 1948. CrossrefMedlineGoogle Scholar14. EvansGrossBaggenstoss HWJBAH: Acute and subacute interstitial pancreatitis: a clinico-pathologic study, Gastroenterology (In press). Google Scholar15. Evans HW: Acute and subacute interstitial pancreatitis, Thesis, Graduate School, University of Minnesota, 1957. Google Scholar16. ComfortSteinberg MWAG: Pedigree of a family with hereditary chronic relapsing pancreatitis, Gastroenterology 21: 54, 1952. CrossrefMedlineGoogle Scholar17. GrossComfort JBMW: Hereditary pancreatitis: report on two additional families, Gastroenterology 32: 829, 1957. CrossrefMedlineGoogle Scholar18. GrossComfortUlrich JBMWJA: The current status of hereditary pancreatitis, Minnesota Med. 41: 78, 1958. MedlineGoogle Scholar19. CollettKennedy RWRL: Chronic relapsing pancreatitis associated with hyperlipemia in an eight year old boy, Proc. Staff Meet., Mayo Clin. 23: 158, 1948. MedlineGoogle Scholar20. Poulsen HM: Familial lipaemia: a new form of lipoidosis showing increase in neutral fats combined with attacks of acute pancreatitis, Acta med. scandinav. 138: 413, 1950. CrossrefMedlineGoogle Scholar21. Dobbs RH: Acute pancreatitis in childhood: report of a case, Lancet 2: 989, 1935. CrossrefGoogle Scholar22. James T: Chronic pancreatitis in childhood, Arch. Dis. Childhood 27: 364, 1952. CrossrefMedlineGoogle Scholar23. ShanksActonCottrell JAWCJD: Acute interstitial pancreatitis in a ten year old girl, Canad. M. A. J. 70: 682, 1954. MedlineGoogle Scholar24. SticklerYonemoto GBRH: Acute pancreatitis in children, J. Dis. Child. 95: 206, 1958. MedlineGoogle Scholar25. GrossComfortUlrich JBMWJA: Abnormalities of serum and urinary amino acids in hereditary and nonhereditary pancreatitis, Tr. A. Am. Physicians 70: 127, 1957. MedlineGoogle Scholar26. GrossUlrich JBJA: Unpublished data. Google Scholar27. DawsonStruthers JWJW: Generalised osteitis fibrosa with parathyroid tumour and metastatic calcification: including a critical discussion of the pathological processes underlying osseous dystrophies, Edinburgh M. J. 30: 421, 1923. Google Scholar28. Hanes FM: Hyperparathyroidism due to parathyroid adenoma, with death from parathormone intoxication, Am. J. M. Sc. 197: 85, 1939. CrossrefGoogle Scholar29. Oliver WA: Acute hyperparathyroidism, Lancet 2: 240, 1939. CrossrefGoogle Scholar30. SmithCooke FBRT: Acute fatal hyperparathyroidism, Lancet 2: 650, 1940. CrossrefGoogle Scholar31. RogersKeatingMorlockBarker HMFRCGNW: Primary hypertrophy and hyperplasia of the parathyroid glands associated with duodenal ulcer: report of an additional case with special reference to metabolic, gastrointestinal and vascular manifestations, Arch. Int. Med. 79: 307, 1947. CrossrefGoogle Scholar32. MartinCanseco LJD: Pancreatic calculosis, J. A. M. A. 135: 1055, 1947. CrossrefMedlineGoogle Scholar33. BellArnold GOWT: Primary hyperparathyroidism: report of two unusual cases, Lahey Clin. Bull. 6: 197, 1950. MedlineGoogle Scholar34. Hellström J: Primary hyperparathyroidism: observations in a series of 50 cases, Acta endocrinol. 16: 30, 1954. CrossrefMedlineGoogle Scholar35. Page F: Diagnostic problems: No. 14. A case of malignant melanoma, steatorrhea, Paget's disease and hyperparathyroidism, Arch. Middlesex Hosp. 4: 215, 1954. MedlineGoogle Scholar36. BogdonoffWoodsWhiteEngel MDAHJEFL: Hyperparathyroidism, Am. J. Med. 21: 583, 1956. CrossrefMedlineGoogle Scholar37. Jackson CE: Hereditary hyperparathyroidism associated with recurrent pancreatitis, Clin. Res. Proc. 5: 185, 1957. Google Scholar38. CopeCulverMixterNardi OPJCGGL: Pancreatitis, a diagnostic clue to hyperparathyroidism, Ann. Surg. 145: 857, 1957. CrossrefMedlineGoogle Scholar39. PloughKyle ICLH: Pancreatic insufficiency and hyperparathyroidism, Ann. Int. Med. 47: 590, 1957. LinkGoogle Scholar40. Clinico-pathologic Conference: Primary hyperparathyroidism, pancreatitis and peptic ulcer, Am. J. Med. 23: 953, 1957. CrossrefMedlineGoogle Scholar41. Cope O: Personal communication to the author. Google Scholar42. Dent CE: Personal communication to Plough, I. C., and Kyle, L. H.89 Google Scholar43. KogutMatznerSobel BMJAE: A study of external pancreatic secretion in man, J. Clin. Investigation 15: 393, 1936. CrossrefMedlineGoogle Scholar44. Thomas JE: The external secretion of the pancreas, 1950, Charles C Thomas, Springfield, Illinois. Google Scholar45. DreilingJanowitz DAHD: Exocrine pancreatic secretion: effects of pancreatic disease, Am. J. Med. 21: 98, 1956. CrossrefMedlineGoogle Scholar46. Sinclair IS: Observations on a case of external pancreatic fistula in man, Brit. J. Surg. 44: 250, 1956. CrossrefMedlineGoogle Scholar47. Renner WF: Postoperative acute pancreatitis and lower nephron syndrome, J. A. M. A. 147: 1654, 1951. CrossrefMedlineGoogle Scholar48. WilkeyNoraLagorioBarson JLEFALJ: Acute necrotizing pancreatitis and lower nephron syndrome following transurethral prostatic resection, J. Internat. Coll. Surgeons 19: 322, 1953. MedlineGoogle Scholar49. Morris WR: Pancreatic fat necrosis following subtotal thyroidectomy, J. A. M. A. 100: 1594, 1933. CrossrefGoogle Scholar50. Gogol LJ: Hemorrhagic pancreatitis following thyroidectomy, California Med. 47: 255, 1937. Google Scholar50a. FerrisLynnCainBaggenstoss DOTEJCAH: Fatal postoperative pancreatitis, Ann. Surg. 146: 263, 1957. CrossrefMedlineGoogle Scholar51. DreilingRichman DAA: Pancreatitis: a review, J. Mt. Sinai Hosp. 21: 122, 176, 1954. MedlineGoogle Scholar52. MenguyHallenbeckBollmanGrindlay RBGAJLJH: Ductal and vascular factors in etiology of experimentally induced acute pancreatitis, Arch. Surg. 74: 881, 1957. CrossrefGoogle Scholar53. MenguyHallenbeckBollmanGrindlay RBGAJLJH: Intraductal pressures and sphincteric resistance in canine pancreatic and biliary ducts after various stimuli, Surg., Gynec. and Obst. 106: 306, 1958. MedlineGoogle Scholar54. Friedreich N: Diseases of the pancreas, in von Ziemssen, H.: Cyclopaedia of the practice of medicine, Vol. 8, 1878, William Wood and Company, New York, pp. 601-602. Google Scholar55. MyersKeefer WKCS: Acute pancreatic necrosis in acute and chronic alcoholism, New England J. Med. 210: 1376, 1934. CrossrefGoogle Scholar56. WeinerTennant HAR: A statistical study of acute hemorrhagic pancreatitis (hemorrhagic necrosis of pancreas), Am. J. M. Sc. 196: 167, 1938. CrossrefGoogle Scholar57. Clark E: Pancreatitis in acute and chronic alcoholism, Am. J. Digest. Dis. 9: 428, 1942. CrossrefGoogle Scholar58. Carter SJ: Serum amylase findings in chronic alcoholic patients with acute, severe abdominal symptoms, Ann. Surg. 122: 117, 1945. CrossrefMedlineGoogle Scholar59. DomzalskiWedge CABH: Elevated serum amylase in alcoholics, Am. J. Clin. Path. 18: 43, 1948. CrossrefMedlineGoogle Scholar60. EdmondsonBullockMehl HAWHJW: Chronic pancreatitis and lithiasis. I. A clinicopathologic study of 62 cases of chronic pancreatitis, Am. J. Path. 25: 1227, 1949. MedlineGoogle Scholar61. RichmanColp AR: Chronic relapsing pancreatitis: treatment by subtotal gastrectomy and vagotomy, Ann. Surg. 131: 145, 1950. CrossrefMedlineGoogle Scholar62. DreilingRichmanFradkin DAANF: The role of alcohol in the etiology of pancreatitis: a study of the effect of intravenous ethyl alcohol on the external secretion of the pancreas, Gastroenterology 20: 636, 1952. CrossrefMedlineGoogle Scholar63. CattellWarren RBKW: Surgery of the pancreas, 1953, W. B. Saunders Company, Philadelphia. Google Scholar64. Zollinger RM: Pancreatitis, Postgrad. Med. 15: 323, 1954. CrossrefMedlineGoogle Scholar65. MacKenzie WC: Pancreatitis—fundamental and clinical aspects, a Moynihan Lecture, Bull. Am. Coll. Surgeons 40: 23, 1955. MedlineGoogle Scholar66. BockusKalserRothBogochStein HLMHJLALG: Clinical features of acute inflammation of the pancreas: analysis of ninety-four attacks in seventy-eight patients, Arch. Int. Med. 96: 308, 1955. CrossrefGoogle Scholar67. BrooksThomas FPJE: The effect of alcohol on canine external pancreatic secretion, Gastroenterology 23: 36, 1953. CrossrefMedlineGoogle Scholar68. GrossHallenbeck JBGA: Chronic relapsing pancreatitis despite achlorhydria: report of five cases and consideration of pathogenesis, unpublished data. Google Scholar69. Dreiling DA: Effect of histamine and histalog (Gastramine) on pancreatic secretion, Gastroenterology 27: 334, 1954. CrossrefMedlineGoogle Scholar70. Johnson WM: Subtotal gastrectomy in the treatment of chronic recurrent pancreatitis, Gastroenterology 14: 590, 1950. CrossrefGoogle Scholar71. McClure CW: Functional activities of the pancreas and liver: a study of objective methods for the estimation of function levels in health and disease, 1937, Medical Authors' Publishing Co., New York. Google Scholar72. McClureJones CWCM: Studies in pancreatic function: the enzyme concentration of duodenal contents in pathological conditions involving the pancreas, liver and stomach, Boston M. and S. J. 187: 909, 1922. CrossrefGoogle Scholar73. Christiansen T, quoted by McClure, C. W.;71 also Thomas, J. E.44 Google Scholar74. Wijnhausen OJ: Ueber Xanthomatose in einem Falle rezidivierender Pankreatitis, Berl. klin. Wchnschr. 2: 1268, 1921. Google Scholar75. Joel E: Zur Klinik der Lipämie, Ztschr. f. klin. Med. 100: 46, 1924. Google Scholar76. BinetBrocqUngar LPG: Le syndrome humoral de la pancréatite hémorragique, Presse méd. 1: 848, 1929. Google Scholar77. Marcus M: The pancreas and intermediate fat metabolism: observations on disturbances of the fat metabolism with temporary lipaemia in acute pancreatic diseases, Folia clin. orient. 1: 127, 1937. Google Scholar78. Root HF: Diabetic coma and acute pancreatitis with fatty livers, J. A. M. A. 108: 777, 1937. CrossrefGoogle Scholar79. KlatskinGordon GM: Relationship between relapsing pancreatitis and essential hyperlipemia, Am. J. Med. 12: 3, 1952. CrossrefMedlineGoogle Scholar80. TourtellotteTyler CRRD: Hyperlipemia associated with diabetes mellitus and pancreatitis: a case report with autopsy, Ann. Int. Med. 45: 691, 1956. LinkGoogle Scholar81. AdlersbergWangHimes DCH: Idiopathic hyperlipemia and recurrent pancreatitis, American Gastroenterological Association, 57th Annual Meeting 1956, pp. 43-44. Google Scholar82. AlbrinkKlatskin MJG: Lactescence of serum following episodes of acute alcoholism and its probable relationship to acute pancreatitis, Am. J. Med. 23: 26, 1957. CrossrefMedlineGoogle Scholar83. Brunner W: Beitrag zur Pankreatogenen Lipämie, Klin. Wchnschr. 14: 1853, 1935. CrossrefGoogle Scholar84. GardnerFawcett CEB: Acute pancreatitis with hyperlipemia, Surgery 27: 512, 1950. Google Scholar85. Coffey RJ: Unusual features of acute pancreatic disease, Ann. Surg. 135: 715, 1952. CrossrefMedlineGoogle Scholar86. AlbrinkManPeters MJEBJP: The relation of neutral fat to lactescence of serum, J. Clin. Investigation 34: 147, 1955. CrossrefMedlineGoogle Scholar87. MillenRussEderBarr RSEMHADP: Pregnancy complicated by hyperlipemia, Am. J. Obst. and Gynec. 71: 326, 1956. CrossrefMedlineGoogle Scholar88. OrvisEvans HHJM: Serum lipids and lipid enzymes in acute pancreatitis with lipemia, Clin. Res. Proc. 5: 197, 1957. Google Scholar89. WangParonettoAdlersberg CIFD: Hyperlipemia and pancreatitis: in man and in experimental animals, Clin. Res. Proc. 5: 197, 1957. Google Scholar90. EdmondsonFields HAIA: Relation of calcium and lipids to acute pancreatic necrosis: report of fifteen cases, in one of which fat embolism occurred, Arch. Int. Med. 69: 177, 1942. CrossrefGoogle Scholar91. EdmondsonBerneHomannWertman HACJREM: Calcium, potassium, magnesium and amylase disturbances in acute pancreatitis, Am. J. Med. 12: 34, 1952. CrossrefMedlineGoogle Scholar92. BinetBrocq LP: La lactescence du sérum sanguin au cours de la pancréatite hémorragique (étude expérimentale), Paris méd. 71: 489, 1929. Google Scholar93. Adlersberg D: Hormonal influences on the serum lipids, Am. J. Med. 23: 769, 1957. CrossrefMedlineGoogle Scholar94. Wiesel J: Ueber Leberveränderungen bei multipler abdomineller Fettgewebsnekrose und Pankreatitis haemorrhagica, Mitt. a. d. Grenzgeb. d. Med. u. Chir. 14: 487, 1905. Google Scholar95. Lynch MJ: Nephrosis and fat embolism in acute hemorrhagic pancreatitis, Arch. Int. Med. 94: 709, 1954. CrossrefGoogle Scholar96. Mueller , quoted by Marcus, M.77 Google Scholar97. CarenCarbo RL: Pancreatic alpha-cell function in relation to cholesterol metabolism, J. Clin. Endocrinol. 16: 507, 1956. CrossrefGoogle Scholar98. OrvisEvans HHJM: Lipase activation by heparin and phosphorylated hesperidin, Clin. Res. Proc. 5: 198, 1957. Google Scholar99. HoltAylwardTimbres LEFXHG: Idiopathic familial lipaemia, Bull. Johns Hopkins Hosp. 64: 279, 1939. Google Scholar100. BloomfieldShenson ALB: The syndrome of idiopathic hyperlipemia with crises of violent abdominal pain, Stanford M. Bull. 5: 185, 1947. MedlineGoogle Scholar101. KoszalkaLevin MFJJ: Idiopathic hyperlipemia, Ann. Int. Med. 33: 473, 1950. LinkGoogle Scholar102. MovittGerstlSherwoodEpstein ERBFCC: Essential hyperlipemia, Arch. Int. Med. 87: 79, 1951. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, Minnesota*Presented in abridged form at the Thirty-ninth Annual Session of The American College of Physicians, Atlantic City, New Jersey, May 1, 1958.From the Section of Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota.The Mayo Foundation, Rochester, Minnesota, is a part of the Graduate School of the University of Minnesota.Requests for reprints should be addressed to Section of Publications, Mayo Clinic, Rochester, Minnesota. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPrevalence of primary painless chronic pancreatitis: A systematic review and meta-analysisZieve's Syndrome: an Unusual Cause of AnemiaHemolytic anemia in alcoholic liver diseasePrevalence of Splanchnic Vein Thrombosis in Pancreatitis: A Systematic Review and Meta-Analysis of Observational StudiesFurther Observations on the Hereditary form of PancreatitisPrimary hyperparathyroidismCationic Trypsinogen Mutations and PancreatitisCationic trypsinogen mutations and pancreatitisAcute PancreatitisHereditäre PankreatitisThe use of epidemiology, scientific data, and regulatory authority to determine risk factors in cancers of some organs of the digestive systemFollow-up of Chronic Pancreatitis. Methodological ConsiderationsDuodenal calcium outputs in health and pancreatic disease.Hereditary pancreatitis in England and Wales.Angeborene Fehlbildungen des PankreasDiabetes mellitus and primary hyperparathyroidismA British family with herediatary pancreatitis.Hereditary pancreatitis in a kinship associated with portal vein thrombosisExtrahepatic Portal Hypertension Caused by Chronic PancreatitisGEORGE F. LONGSTRETH, M.D., ALBERT D. NEWCOMER, M.D., PAUL A. GREEN, M.D.Familial Hyperlipoproteinemia and Exocrine PancreasChronic PancreatitisWILLIAMSON B. STRUM, M.D., HOWARD M. SPIRO, M.D.Hereditary Pancreatitis A Kindred Without Gross AminoaciduriaPAUL DAVIDSON, M.D., F.A.C.P., DAVID COSTANZA, M.D., JOHN A. SWIECONEK, M.D., JOHN B. HARRIS, M.D.Familial pancreatitisGeneral remarks and classificationSecretion of Calcium by the Canine PancreasSOME CLINICAL AND CHEMICAL MANIFESTATIONS OF ALCOHOL-INDUCED HYPERLIPAEMIAPancreatitis Associated with Primary HyperparathyroidismAcute PancreatitisThe Pancreas and Systemic DiseaseALCOHOL‐DEPENDENT HYPERLIPÆMIA: A REPORT OF A CASE AND A DISCUSSION OF THE POSSIBLE MECHANISMSUrinary Excretion of Amino Acids in a Kindred with Hereditary Pancreatitis and AminoaciduriaThe Diagnosis and Management of Chronic PancreatitisCoexistence of Pancreatitis and Hyperparathyroidism Use of the Secretin Test in Evaluation of Pancreatic Function before and after Excision of a Parathyroid AdenomaD. J. KURLANDER, M.D., H. F. RASKIN, M.D., J. B. KIRSNER, M.D., PH.D.Pancreatitis associated with hyperparathyroidismHereditary pancreatitisChronic painless pancreatitisChronic Calcific Pancreatitis in a ChildMedical Complications of Acute PancreatitisAcute transient hyperlipemia due to hepatopancreatic damage in chronic alcoholics (Zieve's syndrome)Further Experience with Pancreatitis as a Diagnostic Clue to HyperparathyroidismNewer horizons in the etiology of pancreatitis: Metabolic and endocrinologic factorsAtypical PancreatitisPrimary HyperparathyroidismAcute Hyperparathyroidism and Acute PancreatitisThe Pancreas: Current Contributions of Clinical InterestRecurrent Acute Hyperparathyroidism with Severe Gastrointestinal ManifestationsMultiple Endocrine Adenoma SyndromeHyperparathyroidism and Pancreatitis 1 October 1958Volume 49, Issue 4Page: 796-819KeywordsExcretionGraduate medical educationHydrochloric acidHyperlipidemiaMucous membranesNatural history of diseasePancreasPancreatitisPathogenesisPathogens ePublished: 1 December 2008 Issue Published: 1 October 1958 PDF downloadLoading ...
No takes yet. Share an insight, caveat, or question.
John B. Gross (1958) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: