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The early growth response gene product (Egr-1) is a zinc finger transcription factor (1, 2) first identified because of its characteristic pattern of expression following exposure of cells to mediators associated with growth and differentiation. Egr-1 (also called Zif268, NGF1-A, Krox24, or TIS8) has been termed an immediate-early response protein, based on the brisk kinetics of its induction, within minutes of a stimulus, and
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Yan et al. (2000) studied this question.
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