Key result
The median ∆VA time was significantly shorter in patients with a septal accessory pathway ablated on the right side compared to the left side (12 vs 56 ms, p<0.001).
Why the study?
Septal accessory pathway ablation is challenging, and accessing the left atrium is often decided only after failed right-sided ablation. The authors investigated whether pacing maneuvers could prospectively identify the successful ablation site.
Does the difference between VA time during RV apical pacing versus VA during tachycardia predict the successful site for ablation of septal accessory pathways?
Observational
Does the difference between VA time during RV apical pacing versus VA during tachycardia predict the successful site for ablation of septal accessory pathways?
Absolute Event Rate: 12% vs 56%
p-value: p=<0.001
ΔVA and StimA–VA values during RV apical pacing can accurately predict whether left atrial access is necessary for successful ablation of septal accessory pathways.
∆VA time may guide right- versus left-sided ablation of septal pathways; leaves open prospective validation before routine use.
Introduction Septal accessory pathway (AP) ablation can be challenging due to the complex anatomy of the septal region. The decision to access the left atrium (LA) is often made after failure of ablation from the right. We sought to establish whether the difference between ventriculo‐atrial (VA) time during right ventricular (RV) apical pacing versus the VA during tachycardia would help establish the successful site for ablation of septal APs. Methods Intracardiac electrograms of patients with orthodromic reciprocating tachycardia (ORT) using a septal AP with successful catheter ablation were reviewed. The ∆VA was the difference between the VA interval during RV apical pacing and the VA interval during ORT. The difference in the VA interval during right ventricular entrainment and ORT (StimA–VA) was also measured. Results The median ∆VA time was significantly less in patients with a septal AP ablated on the right side compared with patients with a septal AP ablated on the left side (12 ± 19 vs. 56 ± 10 ms, p < .001). The StimA–VA was significantly different between the two groups (22 ± 14 vs. 53 ± 9 ms, p < .001). The ∆VA and StimA–VA were always 40 ms in patients with non‐decremental septal APs ablated from the right side and always greater than 40 ms in those with septal APs ablated from the left. Conclusion ΔVA and StimA–VA values identified with RV apical pacing in the setting of ORT involving a septal AP predict when left atrial access will be necessary for successful ablation.
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Kanawati et al. (2020) conducted an observational in Orthodromic reciprocating tachycardia (ORT) using a septal accessory pathway. Septal accessory pathway ablated on the right side vs. Septal accessory pathway ablated on the left side was evaluated on Median ∆VA time (difference between VA interval during RV apical pacing and ORT) (p=<0.001). The median ∆VA time was significantly shorter in patients with a septal accessory pathway ablated on the right side compared to the left side (12 vs 56 ms, p<0.001).
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