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Formulate national expert recommendations on dementia care pathways in response to biological diagnostic criteria for Alzheimer's disease and the advent of disease-modifying therapies.

April 16, 2025Neurological SciencesOpen Access

Towards a new Value-based scenario for the management of dementia in Italy: a SINdem delphi consensus study

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Formulate national expert recommendations on dementia care pathways in response to biological diagnostic criteria for Alzheimer's disease and the advent of disease-modifying therapies.
The Steering Committee of the Italian Neurological Society for dementia (SINdem) formulated 20 statements evaluated by 46 experts using a modified three-round Delphi method.
Consensus inclusion required Grade A (≥75% full agreement) or Grade B (≥80% overall agreement with <5% full disagreement), with response consistency evaluated using Cohen's kappa and intraclass correlation coefficients.
All 20 statements reached consensus, with 4 statements (20%) achieving Grade A consensus and 16 statements (80%) achieving Grade B consensus.
Statements established consensus across care organization from early diagnosis to advanced stages, biomarker access, disease-modifying therapy requirements, and clinical management pathways.
A fair degree of response consistency was maintained across all statements despite existing regional healthcare heterogeneity.

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Implication

Delphi consensus study reports expert agreement on biomarker access and disease-modifying therapy pathways in dementia care, highlighting framework updates for clinical practice.

Cite This Study

Marra et al. (2025) studied this question.

synapsesocial.com/papers/6a84353d52e6a46b6a68c22e https://doi.org/10.1007/s10072-025-08143-5

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Implication

Delphi consensus study reports expert agreement on biomarker access and disease-modifying therapy pathways in dementia care, highlighting framework updates for clinical practice.

Towards a new Value-based scenario for the management of dementia in Italy: a SINdem delphi consensus study

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Discussion

Implication

Cite This Study

Towards a new Value-based scenario for the management of dementia in Italy: a SINdem delphi consensus study

Key Points

Discussion

Implication

Cite This Study

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