Key result
Excision of the tumor followed by 6 cycles of chemotherapy resulted in no locoregional or pulmonary recurrence at 11 months follow-up in an 18-year-old female with alveolar soft part sarcoma.
Case Report (n=1)
No
Excision followed by chemotherapy with adriamycin, cyclophosphamide, and vincristine resulted in no recurrence at 11 months in a rare case of alveolar soft part sarcoma of the forearm with pulmonary metastasis.
Suggests potential feasibility of surgical excision plus chemotherapy for rare alveolar soft part sarcomas;.
Alveolar soft part sarcoma (ASPS) is a rare form of soft-tissue sarcoma arising from connective tissue. It is most often seen in adolescents and young adults and has high propensity for recurrence and metastasis. Clinically, it mimics haemangioma or arteriovenous malformations. In our case report, an 18-year-old female presented with markedly vascular tumour in the left forearm, for which excision biopsy was done. Histopathological report revealed ASPS. The patient was screened for metastasis. Ultrasound abdomen, computed tomography (CT) chest, CT brain and whole-body skeletal survey was done. The patient was found to have bilateral pulmonary metastasis. The patient was given 6 cycles of chemotherapy with adriamycin, cyclophosphamide and vincristine. There was no locoregional and pulmonary recurrence for 11 months after being treated by excision of the tumour followed by chemotherapy.
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Asokan et al. (2017) conducted a case report in Alveolar soft part sarcoma (n=1). Tumor excision followed by chemotherapy (adriamycin, cyclophosphamide, vincristine) was evaluated on Locoregional recurrence and metastasis. Excision of the tumor followed by 6 cycles of chemotherapy resulted in no locoregional or pulmonary recurrence at 11 months follow-up in an 18-year-old female with alveolar soft part sarcoma.
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