Key result
Abnormal physical examination or ECG findings did not increase the rate of abnormal echocardiographic findings compared to universal screening (12.7% vs 18%).
Why the study?
Does targeted echocardiography based on physical exam or ECG screening alter the rate of abnormal echocardiographic findings compared to universal echocardiography in young healthy adults?
Population
1,066 young healthy adults (18- to 20-year-old flight candidates)
Comparison
Targeted echocardiography following referral for… vs Universal echocardiography screening
Design
Cohort
Authors
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Does not support targeted over universal echocardiography; leaves open optimal screening strategy in young healthy adults.
Observational (n=1,066)
Does targeted echocardiography based on physical exam or ECG screening alter the rate of abnormal echocardiographic findings compared to universal echocardiography in young healthy adults?
Absolute Event Rate: 12.7% vs 18%
The presence of abnormal findings on physical examination or ECG screening does not increase the yield of abnormal echocardiographic findings in young healthy adults, highlighting the low overall yield of screening in this population.
Landau et al. (2007) conducted an observational in Healthy adults (n=1,066). Abnormal physical examination or ECG findings vs. Universal screening was evaluated on Abnormal echocardiographic findings. Abnormal physical examination or ECG findings did not increase the rate of abnormal echocardiographic findings compared to universal screening (12.7% vs 18%).
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