May 30, 2008RNAOpen Access

RNA structure-based ribosome recruitment: Lessons from the Dicistroviridae intergenic region IRESes

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Key result

Viral internal ribosome entry sites (IRESes), particularly those of the Dicistroviridae, utilize specific RNA structures to directly recruit ribosomes and bypass canonical translation initiation.

Design

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Authors

JPJennifer S. PfingstenHoward Hughes Medical Institute JKJeffrey S. KieftNew York Structural Biology Center

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Implication

Does not alter clinical practice; leaves open therapeutic targeting of viral IRES structures.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Pfingsten et al. (2008) reported a review. Viral internal ribosome entry sites (IRESes), particularly those of the Dicistroviridae, utilize specific RNA structures to directly recruit ribosomes and bypass canonical translation initiation.

synapsesocial.com/papers/6a8440aba47fb2e1cdb29ec8 https://doi.org/10.1261/rna.987808

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RNA structure-based ribosome recruitment: Lessons from the Dicistroviridae intergenic region IRESes

Discussion

Member takes

Implication

Key Points

Cite This Study

RNA structure-based ribosome recruitment: Lessons from the Dicistroviridae intergenic region IRESes

Discussion

Member takes

Implication

Key Points

Cite This Study

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