Key result
Red ginseng extract powder did not significantly reduce the incidence of primary cancer compared to placebo (RR 0.54; 95% CI 0.23-1.28; P=0.13), although a significant reduction was observed in males.
Why the study?
Does red ginseng extract powder prevent the incidence of human primary cancer in chronic atrophic gastritis patients?
Population
643 chronic atrophic gastritis patients in four hospitals in Zhejiang Province, China
Comparison
Red ginseng extract powder administered orally… vs Placebo
Design
RCT, randomized, double-blinded
Follow-up
11 years (3 years treatment and 8 years follow-up)
Authors
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Red ginseng extract does not reduce primary cancer incidence overall; leaves open a possible male-specific benefit requiring confirmation in larger trials.
RCT (n=643)
Double-blind
Randomized
Yes
Does red ginseng extract powder prevent the incidence of human primary cancer in chronic atrophic gastritis patients?
Relative Risk: 0.54 (95% CI 0.23–1.28)
p-value: p=0.13
Long-term administration of red ginseng extract powder significantly reduced the incidence of non-organ-specific human cancers in male patients with chronic atrophic gastritis.
Yun et al. (2010) conducted an RCT in Chronic atrophic gastritis (n=643). Red ginseng extract powder vs. Placebo was evaluated on Incidence of human primary cancer (RR 0.54, 95% CI 0.23-1.28, p=0.13). Red ginseng extract powder did not significantly reduce the incidence of primary cancer compared to placebo (RR 0.54; 95% CI 0.23-1.28; P=0.13), although a significant reduction was observed in males.
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