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August 8, 2007New England Journal of Medicine

Prophylactic Treatment for Prevention of Joint Disease in Hemophilia — Cost versus Benefit

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GRG. RoosendaalGoethe University FrankfurtFLFloris P. J. G. LafeberUtrecht University

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Roosendaal et al. (2007) studied this question.

synapsesocial.com/papers/6a8445c984161f555bc52845https://doi.org/10.1056/nejme078098
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The impact of prophylactic treatment on children with severe haemophilia1996 · 189 citations
  2. 2Haemophilic arthropathy resembles degenerative rather than inflammatory joint disease1999 · 136 citations
  3. 3When should prophylactic treatment in patients with haemophilia A and B start?— The German experience1998 · 156 citations
  4. 4Prophylaxis with Factor Concentrates in Preventing Hemophilic Arthropathy1991 · 138 citations
  5. 5Pathogenesis of haemophilic arthropathy2006 · 271 citations