Key result
Recurrent myocardial infarction after discharge for acute myocardial infarction was associated with a significantly higher risk of all-cause mortality compared to those without recurrence (15.9% vs 6.3%; HR 2.206).
Population
7,870 patients who survived acute myocardial infarction and were discharged alive, median age 66.2 years…
Design
Cohort
Follow-up
median 3.9 years
Authors
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Recurrent MI flags high-mortality post-AMI patients for closer surveillance; leaves open whether preventive interventions improve survival.
Cohort (n=7,870)
Yes
Hazard Ratio: 2.206 (95% CI 1.56–3.122)
Absolute Event Rate: 15.9% vs 6.3%
p-value: p=<0.001
In post-AMI patients treated in the PCI era, recurrent MI occurs at a relatively low rate but is strongly predicted by diabetes, prior MI, and advanced age, and is associated with a more than two-fold increased risk of subsequent mortality.
Nakatani et al. (2013) conducted a cohort in Acute Myocardial Infarction (n=7,870). Recurrent myocardial infarction vs. No recurrent myocardial infarction was evaluated on All-cause mortality (HR 2.206, 95% CI 1.560-3.122, p=<0.001). Recurrent myocardial infarction after discharge for acute myocardial infarction was associated with a significantly higher risk of all-cause mortality compared to those without recurrence (15.9% vs 6.3%; HR 2.206).
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