Key result
Pre-CABG right ventricular dysfunction (RVFAC <= 35%) in patients with severe LVSD was associated with longer mechanical ventilation (12 vs 1 days, P<0.01) and 100% cardiac mortality within 2 years.
Why the study?
Does pre-cardiopulmonary bypass right ventricular dysfunction predict poor outcomes in patients with severe left ventricular systolic dysfunction undergoing CABG?
Population
41 patients with severe left ventricular systolic dysfunction scheduled for nonemergent coronary artery…
Comparison
Pre-cardiopulmonary bypass right ventricular… vs Pre-cardiopulmonary bypass normal or mildly…
Design
Cohort
Follow-up
Up to 4 years
Authors
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RV dysfunction signals high-risk severe LVSD CABG patients; hypothesis-generating, prospective trials needed before practice change.
Cohort (n=41)
Does pre-cardiopulmonary bypass right ventricular dysfunction predict poor outcomes in patients with severe left ventricular systolic dysfunction undergoing CABG?
Absolute Event Rate: 4.1% vs 12.5%
p-value: p=0.03
Pre-cardiopulmonary bypass right ventricular dysfunction (RVFAC <= 35%) is strongly associated with increased perioperative morbidity and long-term mortality in patients with severe LVSD undergoing CABG.
Maslow et al. (2002) conducted a cohort in severe left ventricular systolic dysfunction (LVSD) undergoing coronary artery bypass grafting (CABG) (n=41). Pre-CABG right ventricular dysfunction (RVFAC <= 35%) vs. RVFAC > 35% was evaluated on change in LVEF immediately after CPB (p=0.03). Pre-CABG right ventricular dysfunction (RVFAC <= 35%) in patients with severe LVSD was associated with longer mechanical ventilation (12 vs 1 days, P<0.01) and 100% cardiac mortality within 2 years.
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