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May 1, 1999Journal of Medicinal ChemistryOpen Access

Synthesis of Novel Phenserine-Based-Selective Inhibitors of Butyrylcholinesterase for Alzheimer's Disease

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Authors

QYQian‐sheng YuLiaoning University of TechnologyHHHarold W. HollowayNational Institutes of HealthTUTadanobu UtsukiPurdue University West Lafayette

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Yu et al. (1999) studied this question.

synapsesocial.com/papers/6a8450234d02f4f0268d7b18https://doi.org/10.1021/jm980459s
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Phenserine, a Novel Anticholinesterase Related to Physostigmine: Total Synthesis and Biological Properties1996 · 41 citations
  2. 2Impact-Induced Cleaving and Melting of Alkali-Halide Nanocrystals1991 · 176 citations
  3. 3Acetylcholinesterase: enzyme structure, reaction dynamics, and virtual transition states1987 · 1,083 citations
  4. 4Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment1991 · 4,490 citations