Key result
Increasing body mass index was strongly associated with angiotensin-dependent control of the renal circulation, measured by renal plasma flow response to captopril (r=0.55; P<0.0001).
Why the study?
Does body mass index correlate with angiotensin-dependent control of the renal circulation in healthy humans?
Population
100 healthy, normotensive subjects in balance on a high-salt diet
Design
Cross-sectional
Authors
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BMI-associated angiotensin dependence may link obesity to renal disease; hypothesis-generating and should not yet change practice.
Cross-Sectional (n=100)
Does body mass index correlate with angiotensin-dependent control of the renal circulation in healthy humans?
Effect estimate: r=0.55
p-value: p=<0.0001
Increasing body mass index is strongly associated with angiotensin-dependent control of the renal circulation, suggesting a mechanism by which obesity contributes to renal disease.
Ahmed et al. (2005) conducted a cross-sectional in Healthy, normotensive (n=100). Body mass index was evaluated on Renal plasma flow response to captopril (r=0.55, p=<0.0001). Increasing body mass index was strongly associated with angiotensin-dependent control of the renal circulation, measured by renal plasma flow response to captopril (r=0.55; P<0.0001).
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