Reducing CKD burden in Europe: first make the elephant apparent!

Q: What is the clinical evidence from this study?

Study design: Editorial. Population: Chronic kidney disease (CKD). Intervention: Proactive primary care CKD screening program (serum creatinine/eGFR, urinary ACR, urine dipstick for haemoglobinuria, and haemoglobin level).

Q: What does this research mean for the field?

Proactive primary care screening in high-risk patients aged 55-75 is necessary to overcome the widespread underdiagnosis of chronic kidney disease and enable timely implementation of protective therapies. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

Luca De Nicola; Roberto Minutolo; Giuseppe Grandaliano

doi:10.1093/ckj/sfaf182

June 12, 2025Clinical Kidney JournalOpen Access

Reducing CKD burden in Europe: first make the elephant apparent!

View Full Paper

Ask AI

Bookmark

Share

Figures

Structured PICO

P

Population

Proposed national primary care screening program in Italy targeting high-risk adults aged 55-75 years with hypertension, diabetes mellitus, heart disease, or obesity to improve early detection of chronic kidney disease.

I

Intervention

Proactive CKD screening program implemented in primary care (general practitioner offices) utilizing serum creatinine (to estimate GFR), urinary albumin–creatinine ratio (ACR), urine dipstick testing for haemoglobinuria, and haemoglobin levels, followed by confirmatory repeat testing after 3–6 months and referral of progressive or severe CKD to nephrology clinics.

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

This editorial highlights the WHO's 2025 prioritization of kidney health and outlines an Italian legislative initiative to implement targeted primary care CKD screening in high-risk patients aged 55–75 years to enable early cardiorenal protective therapy.

Abstract

Luca De Nicola, Roberto Minutolo, Giuseppe Grandaliano; Reducing CKD burden in Europe: first make the elephant apparent!, Clinical Kidney Journal, , sfaf18

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Nicola et al. (2025) conducted an editorial in Chronic kidney disease (CKD). Proactive primary care CKD screening program (serum creatinine/eGFR, urinary ACR, urine dipstick for haemoglobinuria, and haemoglobin level) was evaluated.

synapsesocial.com/papers/6a845dfc356b31aeb3f304a1 https://doi.org/10.1093/ckj/sfaf182

View Full Paper

Ask AI

Bookmark

Share

Reducing CKD burden in Europe: first make the elephant apparent!

Figures

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Reducing CKD burden in Europe: first make the elephant apparent!

Figures

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading