Key result
A preoperative E/e' ratio >15 was an independent predictor of postoperative acute kidney injury in patients undergoing off-pump coronary artery bypass surgery with preserved LV systolic function (OR 3.01).
Why the study?
Does an elevated preoperative E/e' ratio (>15) predict postoperative acute kidney injury in patients undergoing off-pump coronary artery bypass surgery with preserved LVEF?
Population
585 adult patients who underwent off-pump coronary artery bypass surgery with preserved left ventricular…
Comparison
Preoperative E/e' ratio >15 vs Preoperative E/e' ratio ≤15
Design
Cohort
Follow-up
7 postoperative days for AKI, up to 1 year for mortality
Authors
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May inform perioperative AKI risk stratification in preserved-LVEF off-pump CABG; hypothesis-generating and leaves open need for prospective validation.
Observational (n=585)
No
Does an elevated preoperative E/e' ratio (>15) predict postoperative acute kidney injury in patients undergoing off-pump coronary artery bypass surgery with preserved LVEF?
Odds Ratio: 3.01 (95% CI 1.4–6.17)
Absolute Event Rate: 27.2% vs 8.9%
p-value: p=0.006
In patients undergoing off-pump coronary artery bypass surgery with preserved LV systolic function, an elevated preoperative E/e' ratio (>15) is a strong independent predictor of postoperative acute kidney injury.
Hur et al. (2017) conducted an observational in Acute kidney injury after off-pump coronary artery bypass surgery (n=585). Preoperative E/e' ratio >15 vs. Preoperative E/e' ratio ≤15 was evaluated on Acute kidney injury (AKI) by KDIGO criteria within 7 postoperative days (OR 3.01, 95% CI 1.40-6.17, p=0.006). A preoperative E/e' ratio >15 was an independent predictor of postoperative acute kidney injury in patients undergoing off-pump coronary artery bypass surgery with preserved LV systolic function (OR 3.01).
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