Key result
Type 2 diabetes mellitus worsens the prognosis of planned myocardial revascularization, while novel pharmacological strategies like SGLT2 inhibitors and GLP-1 agonists may help manage these risks.
Why the study?
To review issues surrounding planned percutaneous coronary intervention in patients with type 2 diabetes mellitus, including the pathogenetic basis of poor prognosis and new approaches to pharmacological risk correction.
The review highlights the increased risks of adverse outcomes after PCI in patients with type 2 diabetes and emphasizes the importance of optimal glycemic control and novel antidiabetic therapies to mitigate these risks.
The article is a literature review devoted to issues of planned percutaneous coronary intervention for patients with type 2 diabetes mellitus. Pathogenetic base of poor prognosis and new ways to pharmacological risk correction are described. The article highlights the trends in the incidence of carbohydrate metabolism disorders, their role in the development of complications of myocardial revascularization. The results of studies comparing different tactics of revascularization and their results in patients with different status of carbohydrate metabolism are presented. The article discusses the methods of risk management within percutaneous coronary revascularization, the role of glycemic metabolism in the risk of an poor prognosis of myocardial revascularization, describes the results of clinical trials of new drugs that can have a positive effect on the prognosis of revascularization in patients with carbohydrate metabolism disorders.
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Кочергина et al. (2019) conducted a review in Type 2 diabetes mellitus and coronary artery disease. Percutaneous coronary intervention and novel pharmacological therapies was evaluated. Type 2 diabetes mellitus worsens the prognosis of planned myocardial revascularization, while novel pharmacological strategies like SGLT2 inhibitors and GLP-1 agonists may help manage these risks.
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