Key result
Increased body weight in hypertensive non-diabetic patients was associated with greater ventricular mass, which correlated with lower ejection fraction values and altered filling patterns (P=0.05, 0.1).
Why the study?
Hypertension and obesity induce remodeling and diastolic dysfunction that precede systolic heart failure, prompting evaluation of the relation between geometry and ventricular function in hypertensive non-diabetic and obese patients.
Cross-Sectional (n=88)
p-value: p=0.05, 0.1
In non-diabetic hypertensive patients, increased body weight is associated with altered ventricular geometry and diastolic dysfunction, which may precede systolic impairment.
Body weight may link to preclinical ventricular changes in non-diabetic hypertension; leaves open need for longitudinal confirmation before practice implications.
Hypertension and obesity make changes in the heart that are known as remodeling and diastolic dysfunction. These changes are the beginning of a later sistolic heart failure. Objectives Searching for the relation between geometry and ventricular function in hypertensive non diabetic and obese patients. 68 women and 20 men were evaluated by doppler- echocardiography. All patients had a normal ejection fraction. Results Ventricular geometry was altered in 53.4% of the subjects and diastolic function in 73.8% respectively. As body weight increased the ventricular mass, relative wall thickness, left atrial dimension and end diastolic volumes increased too. Overweight and obesity were found in 62.5% of the sample. A concentric left ventricular hypertrophy was present in 27.2% of the patients. An excentric left ventricular hypertrophy was found in 14.7% of them and 46.6% had a normal geometry. Eyection fraction values were lesser in the group with bigger ventricular mass and altered filling patterns. P=0.05, 0.1. Conclusion Arterial hypertension and obesity are risk factors for the development of cardiac abnormalities that lower systolic cardiac function in case of hypertrophy and dilatation are not resolved.
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A. Suarez (2021) conducted a cross-sectional in Hypertension and obesity (n=88). Increased body weight and ventricular mass was evaluated on Ejection fraction values and ventricular geometry/diastolic function (p=0.05, 0.1). Increased body weight in hypertensive non-diabetic patients was associated with greater ventricular mass, which correlated with lower ejection fraction values and altered filling patterns (P=0.05, 0.1).
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