Key result
Patients with NAFLD had significantly higher epicardial fat thickness (0.58 vs 0.36 cm, P<0.001) and carotid intima-media thickness (0.64 vs 0.52 mm, P<0.001) compared to matched controls.
Population
57 patients with biopsy-proven nonalcoholic fatty liver disease and 30 age-matched and sex-matched controls
Design
Case-control
Authors
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May indicate elevated subclinical atherosclerosis risk in NAFLD; leaves open need for prospective validation before screening changes.
Case-Control (n=87)
Absolute Event Rate: 0.58% vs 0.36%
p-value: p=<0.001
Epicardial fat thickness and carotid intima-media thickness are significantly increased in patients with NAFLD and are independently correlated, suggesting an increased risk of subclinical atherosclerosis.
Çolak et al. (2012) conducted a case-control in Nonalcoholic fatty liver disease (NAFLD) (n=87). Nonalcoholic fatty liver disease (NAFLD) vs. Age- and sex-matched controls was evaluated on Epicardial fat thickness (EFT) (p=<0.001). Patients with NAFLD had significantly higher epicardial fat thickness (0.58 vs 0.36 cm, P<0.001) and carotid intima-media thickness (0.64 vs 0.52 mm, P<0.001) compared to matched controls.
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