Key result
Erectile dysfunction was associated with significantly worse global left ventricular longitudinal strain (-18.2 vs -21.1; p<0.001) and circumferential strain (-19.5 vs -21.9; p<0.001) than controls.
Why the study?
The study investigated the association between epicardial fat tissue and left ventricular systolic function assessed by speckle tracking echocardiography in patients with erectile dysfunction.
Does epicardial fat tissue thickness predict subclinical left ventricular dysfunction in patients with erectile dysfunction?
Case-Control (n=274)
Does epicardial fat tissue thickness predict subclinical left ventricular dysfunction in patients with erectile dysfunction?
Absolute Event Rate: -18.2% vs -21.1%
p-value: p=<.001
Epicardial fat tissue thickness is associated with subclinical left ventricular systolic dysfunction in patients with erectile dysfunction, highlighting a potential imaging marker for early cardiovascular risk in this population.
EFT thickness may flag subclinical LV dysfunction in ED; leaves open its value for risk stratification pending prospective validation.
Background Erectile dysfunction (ED) is an early form of atherosclerosis and subclinical myocardial dysfunction. Epicardial fat tissue (EFT) is associated with impaired left ventricular (LV) function, even in the absence of cardiovascular disease. The aim of this study was to investigate the association between EFT and LV systolic function in patients with erectile ED by speckle tracking echocardiography (2D-STE) method.Methods A total of 129 consecutive patients with ED were compared with 145 age- and sex-matched control subjects. ED was evaluated using the International Index of Erectile Function questionnaire. Thickness of EFT was measured by TTE. Global LV longitudinal strain (LV-GLS) and global LV circumferential strain (LV-GCS) were measured by 2D-STE method.Results The EFT thickness was significantly higher in the patients with ED (p <.01). LV-GLS and LV-GCS were revealed to be more deterioration in the ED group compared to controls (−18.2 ± 2.7 vs. (−21.1 ± 3.9, p<.001; −19.5 ± 4.1 vs. −21.9 ± 3.9, p<.001, respectively). It has been shown that EFT thickness is an independent predictor of LV dysfunction.Conclusions These results indicate that EFT thickness is associated with subclinical LV systolic dysfunction in patients with ED.
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Eren et al. (2021) conducted a case-control in Erectile dysfunction (n=274). Erectile dysfunction vs. Age- and sex-matched control subjects was evaluated on Global LV longitudinal strain (LV-GLS) and global LV circumferential strain (LV-GCS) (p=<.001). Erectile dysfunction was associated with significantly worse global left ventricular longitudinal strain (-18.2 vs -21.1; p<0.001) and circumferential strain (-19.5 vs -21.9; p<0.001) than controls.
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