Key result
The incidence of congenital heart disease in neonates undergoing non-cardiac surgery was 15.5%, and was significantly associated with dysmorphic features, congenital abnormalities, and abnormal ECG.
Why the study?
Data on concurrent CHD in neonates undergoing non-cardiac surgery are scarce, especially in resource-limited settings where preoperative echocardiography is not always available.
Population
198 neonates undergoing non-cardiac surgery during their first 28 days of life
Comparison
Neonates receiving perioperative echocardiography (103) vs those not referred
Design
Single-center retrospective cohort study
Authors
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Supports avoiding preoperative echocardiography in low-risk neonates; hypothesis-generating for resource-limited settings.
Cohort (n=198)
No
In resource-limited settings, neonates lacking dysmorphic features, congenital abnormalities, abnormal chest radiographs, or abnormal ECGs have a low likelihood of CHD and may safely undergo time-sensitive non-cardiac surgery without a preoperative echocardiogram.
Krause et al. (2025) conducted a cohort in Neonates undergoing non-cardiac surgery (n=198). Clinical features and special investigations (dysmorphic features, congenital abnormalities, abnormal CXR, abnormal ECG) vs. Absence of these features was evaluated on Incidence of congenital heart disease (CHD). The incidence of congenital heart disease in neonates undergoing non-cardiac surgery was 15.5%, and was significantly associated with dysmorphic features, congenital abnormalities, and abnormal ECG.
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