The toxicity, leachability, and site of uptake of the herbicide 2-chloro-2',6'-diethyl-N-(methoxymethyl) acetanilide (hereinafter referred to as CP 50144) were studied in different soils. Two inches of water leached most of the compound to a soil depth of 2 to 3 inches, when applied at rates of 1 and 2 kg/ha. The inherent toxicity of CP 50144 to cotton ( Gossypium hirsutum L., var. Acala 4-42) was studied in culture solution. The herbicide was most toxic to cotton when the entire root system of the crop was exposed to soil treated with CP 50144; reduction of weight of seedlings was accompanied by severe inhibition of root growth. On the other hand, only a slight reduction in growth rate was noticed when only the shoot zone of cotton was exposed to the herbicide.
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Y. Eshel (1969) studied this question.
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