Asymmetric Assembly of Aromatic Rings To Produce Tetra‐ortho‐Substituted Axially Chiral Biaryl Phosphorus Compounds

Densely substituted title compounds can be obtained efficiently through an enantioselective [2+2+2] cycloaddition catalyzed by a cationic RhI/H8-binap complex (see scheme). This method is highly practical in view of the ready access to substrates, mild reaction conditions, operational simplicity, and high catalytic activity. cod=1,5-cyclooctadiene; H8-binap=2,2′-bis(diphenylphosphanyl)-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-binaphthyl; Ts=p-toluenesulfonyl.