Population
Mouse embryo fibroblasts (L-929 strain) and HeLa S3 cells
Comparison
Dimethylsulfoxide to dissociate polyribosomes… vs Me2SO plus cycloheximide versus Me2SO alone
Design
Preclinical
Authors
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Does not inform clinical practice; leaves open 7S RNA's potential role in translation pending human studies.
The 7S RNA species found in oncornaviruses and normal cells is associated with cellular polyribosomes, suggesting a role in the translation process.
Walker et al. (1974) studied this question.
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