Key result
Pre-hospital administration of nitroglycerin was independently associated with a reduced risk of death within 1 year in patients with acute myocardial infarction (HR 0.40).
Why the study?
Does pre-hospital pharmacological intervention reduce 1-year mortality in patients with acute myocardial infarction?
Observational (n=1,726)
No
Does pre-hospital pharmacological intervention reduce 1-year mortality in patients with acute myocardial infarction?
Hazard Ratio: 0.4 (95% CI 0.23–0.7)
p-value: p=0.001
In a retrospective cohort of AMI patients, pre-hospital administration of nitroglycerin, but not aspirin, was independently associated with a reduced risk of 1-year mortality, though this may reflect selection bias for lower-risk patients.
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Strandmark et al. (2015) conducted an observational in Acute myocardial infarction (n=1,726). Pre-hospital nitroglycerin vs. No pre-hospital nitroglycerin was evaluated on Death within 1 year (HR 0.40, 95% CI 0.23-0.70, p=0.001). Pre-hospital administration of nitroglycerin was independently associated with a reduced risk of death within 1 year in patients with acute myocardial infarction (HR 0.40).
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