Acute Glomerulonephritis in the Guillain-Barré-Strohl Syndrome

From February 1969 through March 1972, nine cases of the Guillain-Barré-Strohl syndrome were seen. In all nine patients there was evidence of acute glomerulonephritis, and in eight histological confirmation was obtained. The clinical manifestations of renal disease were hypertension or microscopic hematuria, or both, found only after repeated examinations. In one patient who showed clear-cut histologic changes, there were no clinical or laboratory findings of nephritis. The patients were followed for up to 3 years after the initial episode, and control biopsies in two patients showed progressive changes towards chronicity. The data suggest that acute nephritis is frequently associated with idiopathic polyneuroradiculitis.