Key result
Negative emotions can instigate a chronic stress response, heightening sympathetic nervous system activity and increasing vulnerability to cardiovascular diseases.
Why the study?
The underlying pathophysiological mechanisms and clinical implications of the impact of negative emotions on the cardiovascular system remain inadequately defined.
Negative emotions instigate a chronic stress response that increases vulnerability to cardiovascular diseases, highlighting the need for targeted lifestyle interventions.
Supports screening for negative emotions in CVD risk evaluation; leaves open causal impact and intervention efficacy in prospective trials.
Negative emotions can have a significant impact on individuals, which then influences their cardiovascular system. However, the underlying pathophysiological mechanisms and clinical implications of this association remain inadequately defined. A narrative review of pertinent literature was conducted to examine the pathophysiology, clinical manifestations, and treatment related to the interplay between emotions and conditions such as takotsubo cardiomyopathy, atherosclerosis, acute plaque rupture, and cardiac arrhythmias. Negative emotions can instigate a chronic stress response, which in turn heightens sympathetic nervous system activity and increases vulnerability to cardiovascular diseases. This intricate relationship between emotional states and cardiovascular health underscores the necessity for targeted lifestyle interventions and clinical strategies aimed at mitigating the adverse effects of negative emotions.
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Al-Rawi et al. (2025) conducted a review in Cardiovascular diseases. Negative emotions was evaluated on Cardiovascular health and diseases (e.g., takotsubo cardiomyopathy, atherosclerosis, acute plaque rupture, cardiac arrhythmias). Negative emotions can instigate a chronic stress response, heightening sympathetic nervous system activity and increasing vulnerability to cardiovascular diseases.
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