Characterizing technical success and clinical outcomes in patients with pulmonary embolism treated with ultrasound-assisted catheter-directed thrombolysis (USAT): a retrospective, single-center cohort study

Figures

• 

  Fig. 1. Inclusion Flowchart. After screening, 109 USAT cases were identified by OPS code, 2 cases were excluded because of use in non-PE patients. Of those 107 cases, in 44 cases TTE imaging before and in 67 after EKOS was available. RV/LV ratio change was calculated in 32 cases. Based on CT images, RV/LV ratio was calculated in 16 cases. Image data before EKOS was available in 91 cases, after EKOS in 17 cases

• 

  Fig. 2. Changes in RV/LV ratio. A RV/LV ratio was significantly reduced based on TTE imaging. B A significant reduction of RV/LV ratio was shown in CT image analysis. C Reduction in RV/LV ratio correlates significantly with RV/LV ratio at baseline. D Bland Altman plot comparing reduction of RV/LV ratio in TTE and CT. CT analysis tend to show a higher reduction in RV/LV ratio

• 

  Fig. 3. Changes in physiological parameters. A Significant differences in blood pressure between the risk groups were observed. Although both groups improved, significant differences remained after 24 h. B Significant differences in the respiratory rate between the risk groups were observed. No significant changes were observed after 24 h. C Significant differences in heart rate at the beginning equalized after 24 h and both groups improved significantly

• 

  Fig. 4. Associated risk factors of intrahospital death and bleeding. A Forest plot comparing odds ratios of clinical risk factors for intrahospital death. High risk, PAPsys, Syncope, Anticoagulation, malignancy, sPESI score, blood pressure, d-dimers and proBNP indicated a higher risk for intrahospital death. B Forest plot comparing odds ratios of clinical risk factors for bleeding. High risk, ECMO, anticoagulation, elevated D-dimer levels and low platelet count indicated an elevated risk for bleeding. Other clinical aspects did not correlate significantly