Why the study?
The relation between hospitalization timing and risk of clinical outcomes among patients with AF with and without stroke remained undetermined.
Does weekend hospitalization compared to weekday hospitalization worsen clinical outcomes in patients with atrial fibrillation?
Does weekend hospitalization compared to weekday hospitalization worsen clinical outcomes in patients with atrial fibrillation?
Among patients with atrial fibrillation, weekend hospitalization combined with stroke is associated with significantly higher risks of rehospitalization and mortality compared to weekday hospitalization without stroke.
Weekend AF hospitalizations with stroke were associated with higher risks; this leaves open whether system factors explain outcomes or warrant targeted trials.
PURPOSE: The relation between hospitalization timing and risk of clinical outcomes among patients with atrial fibrillation (AF) with and without stroke remained undetermined. METHODS: Rehospitalization due to AF, cardiovascular (CV) death and all-cause mortality were the outcomes of interest in this study. Multivariable Cox proportional hazard model was applied to estimate the adjusted hazard ratio (HR) and 95% confidence interval (CI). RESULTS: While considering patients with AF hospitalized during weekdays without stroke as the reference group, patients with AF hospitalized during weekends with stroke had the risk of AF rehospitalization, CV death and all-cause death by 1.48 (95% CI 1.44 to 1.51), 1.77 (95% CI 1.71 to 1.83) and 1.17 (95% CI 1.15 to 1.19) times, respectively. CONCLUSION: Patients with AF hospitalized during weekends with stroke had the worst clinical outcomes.
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Hu et al. (2022) studied this question.
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