Why the study?
Does newly diagnosed Obstructive Sleep Apnoea without known comorbidities increase early atherosclerotic lesions in non-smokers?
Population
40 non-smokers, mean age 50.8 years, 80% male. Key exclusions: mixed or central apnoeas, chronic obstructive…
Comparison
Newly diagnosed Obstructive Sleep Apnoea without… vs Healthy age- and BMI-matched controls without OSA
Design
Case-control
Authors
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No significant CCA-IMT difference in uncomplicated OSA; leaves open whether OSA accelerates early atherosclerosis in low-risk non-smokers.
Does newly diagnosed Obstructive Sleep Apnoea without known comorbidities increase early atherosclerotic lesions in non-smokers?
Patients with newly diagnosed obstructive sleep apnoea without known comorbidities exhibit a non-significant increase in carotid intima-media thickness, suggesting early but not yet statistically significant vascular changes.
P Steiropoulos (2013) studied this question.
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