Sleep-Disordered Breathing and Acute Ischemic Stroke
Key result
Sleep-disordered breathing is common in acute ischemic stroke, improves after the acute phase (P<0.001), and is associated with increased long-term poststroke mortality.
Why the study?
What are the risk factors, treatment response, and long-term outcomes of sleep-disordered breathing in patients with acute ischemic stroke?
Population
152 patients with acute ischemic stroke, mean age 56±13 years.
Design
Cohort
Follow-up
60±16 months
Authors
Discussion
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Member takes
Implication
May warrant screening in acute ischemic stroke; leaves open whether treating sleep-disordered breathing improves survival.
Study Design
Type
Cohort (n=152)
Structured PICO
What are the risk factors, treatment response, and long-term outcomes of sleep-disordered breathing in patients with acute ischemic stroke?
P
Population
152 patients with acute ischemic stroke, mean age 56±13 years.
I
Intervention
Continuous positive airway pressure (CPAP) treatment started acutely in patients with sleep-disordered breathing (AHI ≥15 or AHI ≥10 + Epworth sleepiness score >10).
O
Outcome
Apnea-hypopnea index (AHI) at 3±2 days and 6 months; CPAP compliance, incidence of vascular events, and stroke outcome at 60±16 months.hard clinical
Main Result
p-value: p=<0.001
Cite This Study
Bassetti et al. (2006) conducted a cohort in acute ischemic stroke (n=152). Continuous positive airway pressure (CPAP) was evaluated on Apnea-hypopnea index (AHI) change from acute to subacute phase (p=<0.001). Sleep-disordered breathing is common in acute ischemic stroke, improves after the acute phase (P<0.001), and is associated with increased long-term poststroke mortality.