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A sensitive and reproducible method for assay of antidiuretic activity, described in this paper, yielded accurate measurements in the range 60 to 540 micropressor units of pitressin, corresponding to about 15 to 130 micropressor units of arginine-vasopressin. The method differs from previous techniques mainly in using urine density, rather than urinary flow rates, as the index of response.
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Niels A. Thorn (1957) studied this question.
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