Cyclic nucleotides do not directly modulate mEAG1 and hERG1 channels, suggesting their cyclic nucleotide binding domains may harbor a binding site for an undiscovered ligand.
No takes yet. Share an insight, caveat, or question.
No direct cyclic nucleotide modulation of hERG or EAG channels; leaves open discovery of alternative CNBD ligands.
Brelidze et al. (2009) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: