Antibodieswhich fail to precipitate with the monomeric homologous cytochromes c were elicited in rabbits by the conjugate of bovine y-globulin and cytochrome c (tuna and turkey proteins)or by free monomeric cytochrome c (kangaroo and, in one case, the horse protein).Such antibodies do form precipitates and fix complement when allowed to react with the polymerized homologous antigen.In contrast, antisera elicited by monomeric human, MQCQCQ mulaffa,
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Reichlin et al. (1970) studied this question.
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