The reliability of the mode of carboxylate binding to ortho-phenylenediamine based bis-urea clefts is demonstrated in a variety of systems including a hydrogen bonded tape suggesting that this DDDD-AA supramolecular synthon may find application in crystal engineered systems in the future.
No takes yet. Share an insight, caveat, or question.
Brooks et al. (2005) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: