What question did this study set out to answer?

To assess metabolic adaptations and the synthetic capacity of secretory epithelial cells in goat mammary tissue across pregnancy and lactation.

January 1, 1986ReproductionOpen Access

Metabolic adaptations in goat mammary tissue during pregnancy and lactation

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Authors

CWC WildeNew York University Press AHAlan J. HendersonScottish Environment Protection Agency CKChristopher H. KnightHannah Research Foundation

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Implication

Longitudinal tissue analysis demonstrates sustained cellular synthesis despite falling milk yield in goats, suggesting cell loss rather than reduced function drives late-phase decline.

Key Points

To assess metabolic adaptations and the synthetic capacity of secretory epithelial cells in goat mammary tissue across pregnancy and lactation.
Monitored goat mammary tissue using serial biopsies taken throughout pregnancy and lactation.
Assessed synthetic capacity by measuring enzyme activities per milligram of DNA and culturing mammary explants to evaluate lactose, casein, and total protein synthesis.
Mammary cell differentiation initiated during late pregnancy and completed by week 5 of lactation, matching the timing of peak milk yield.
Enzyme activities per milligram of DNA and explant synthesis rates of lactose and casein remained elevated long after week 5, even as overall milk production declined.

Cite This Study

Wilde et al. (1986) studied this question.

synapsesocial.com/papers/6a8512e123b773525b54dbf8 https://doi.org/10.1530/jrf.0.0760289

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Implication

Longitudinal tissue analysis demonstrates sustained cellular synthesis despite falling milk yield in goats, suggesting cell loss rather than reduced function drives late-phase decline.

Metabolic adaptations in goat mammary tissue during pregnancy and lactation

Discussion

Member takes

Implication

Key Points

Cite This Study

Metabolic adaptations in goat mammary tissue during pregnancy and lactation

Discussion

Member takes

Implication

Key Points

Cite This Study

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