A novel potassium iodide‐catalyzed three‐component synthesis of quinazolines via benzylic CH bonds amination was developed. Commonly used ammonia salt and the sp 3 carbon in commercially available methylarenes were used as nitrogen and C 1 sources, respectively. Mechanistic studies indicated that an aryl aldehyde is involved as a key intermediate in the reaction. magnified image
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Zhao et al. (2014) studied this question.
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