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Literature review examines nimodipine and magnesium sulfate for arterial spasm after cerebral aneurysm rupture, highlighting therapeutic mechanisms.
Vascular spasm in patients with hemorrhage from rupture of cerebral aneurysms is the main cause of adverse outcomes of the disease. One way to treat persistent contraction of cerebral arteries is to use nimodipine and magnesium sulfate. This literature review presents studies on the use of nimodipine and magnesium sulfate in the treatment of vascular spasm, and highlights the main links of pathogenesis and drug action mechanisms.
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Kalinkin et al. (2020) studied this question.
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