In vitro α–glucosidase and α–amylase enzyme inhibitory effects in aqueous extracts of Abelmoscus esculentus (L.) Moench

To provide in vitro evidence for antidiabetic activity through potential inhibition of α -glucosidase and α -amylase enzymes using the aqueous extracts of Abelmoschus esculentus (L.) Moench. (A. esculentus) peel (AAPP) and seed (AASP). The peel and seed of okra was dried under shade and powdered. The powdered peel and seed were used for the preparing the aqueous extract. The aqueous extract (AAPP and AASP) were used for the in vitro study. The AAPP and AASP showed appreciable α -glucosidase [IC50 = (142.69 ± 0.32) μg/mL and (150.47 ± 0.28) μg/mL] and α -amylase [(IC50 = (132.63 ± 0.16) μg/mL and (147.23 ± 0.21) μg/mL] inhibitory effect in a concentration-dependent manner. Thus the present study confirms the hypoglycemic effect in the AAPP and AASP aqueous extracts of A. esculentus. The present study results, gives a clear evidence that A. esculentus has antidiabetic activity.