Single dose Dexamethasone for Postoperative Nausea and Vomiting – a Matched Case-Control Study of Postoperative Infection Risk

235 patients (63 cases, 172 controls) undergoing non-emergency surgery under general anaesthesia in a university trauma centre. Exclusions included immunosuppressive medications, chronic glucocorticoid therapy, cardiac surgical and solid-organ transplantation procedures.

Single intraoperative anti-emetic dose of dexamethasone (4 to 8 mg)

No dexamethasone (exposure comparison in a matched case-control design)

Postoperative infection between one day and one month following the operative proceduresafety