The plasmal and nucleal tests and the histochemical methods for detection of iron, potassium, and acid proteins indicate that changes in quality, quantity, and localization of substances characterize the period of differentiation in the oöcyte of Fundulus. The oöcyte at the end of its growth-period is morphologically very different from the oögonium. Its structural changes are found to be correlated with the metabolic activities leading to food storage. Cytosomal differentiations are conspicuously chemical phenomena in egg-cells.
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Mârza et al. (1937) studied this question.
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