Why the study?
Pulmonary arterial hypertension impacts heart disease outcomes, but its specific clinical impact on patients admitted with atrial fibrillation/atrial flutter, ventricular tachycardia, or a first myocardial infarction needed evaluation to inform risk stratification and management guidelines.
Does underlying pulmonary arterial hypertension worsen in-hospital outcomes in patients admitted for atrial fibrillation, ventricular tachycardia, or first myocardial infarction?
Population
Adults admitted with AF (n=2,292,194), VT (n=241,225), or first MI (n=2,567,159)
Comparison
Secondary diagnosis of PAH vs no PAH
Design
National Inpatient Sample database analysis
Authors
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PAH may raise in-hospital mortality in AF/VT/MI admissions; leaves open prospective validation for risk stratification.
Does underlying pulmonary arterial hypertension worsen in-hospital outcomes in patients admitted for atrial fibrillation, ventricular tachycardia, or first myocardial infarction?
Underlying pulmonary arterial hypertension significantly increases the risk of in-hospital mortality, length of stay, and resource utilization in patients admitted for common acute cardiac conditions.
Siochi et al. (2025) studied this question.
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