Nonmotor symptoms in Parkinson‘s disease: the dark side of the moon

Nonmotor symptoms may appear during the course of Parkinson‘s disease, complicating the advanced phase in particular, but are also common in the premotor phase of Parkinson‘s disease. The appearance of nonmotor manifestations represents a milestone, determining a worse prognosis and lower quality of life; however, they are often misdiagnosed and untreated. The spectrum of nonmotor symptoms encompasses mood disorders, psychosis, dementia, sleep disorders, impulse-control disorders and autonomic dysfunctions. This article describes these nonmotor symptoms and their management.